Section I: Introduction

The role of local governmental health departments in Massachusetts is to promote health and equity, combat disease, increase longevity, and improve the quality of life for all residents of the Commonwealth. Over the past decade, recognition of substance use as a widespread factor that impacts health, and LBOH staff have taken the lead in addressing the needs of people with substance use disorders. Opioid and other substance use and opioid-related deaths remain  critical public health problems in the Commonwealth. While opioid-related deaths substantially dropped for the first time in nearly two decades between 2023 and 2024 from 2,114 to 1,336, respectively, the number of annual deaths remains 2.7 times higher than observed in the year 2000.

This toolkit will prepare local health departments to respond to the opioid and other substance use in their communities. We know that prevention and interventions are most successful when they are well-matched to the needs and conditions of the community. This one-stop reference guide contains the information local health departments need to create and implement public health approaches that make a difference.

Specifically, these resources will help local health departments:

  • Understand the scope of the opioid epidemic in your community and its impact on the health of community members, including those members historically excluded from public health initiatives.
  • Identify opportunities for leading and/or participating in public health initiatives dedicated to addressing substance use and other behavioral health problems.
  • Learn how to reduce both the individual and environmental factors shown to increase the risk of new opioid or other drug use, and promote those factors that protect against initiation of substance use.
  • Identify and collaborate with substance use prevention partners in your community or region to ensure alignment of services.
  • Improve access to treatment services and linkages among services for individuals with opioid/substance use disorder (OUD/SUD) when those individuals reach out to the health department.
  • Recognize opportunities for health department staff to reduce barriers to care and address the stigma associated with OUD/SUD.

This resource was designed for use by Massachusetts municipalities. However, much of the content is appropriate for communities outside of the Commonwealth.

How This Toolkit Is Organized

This toolkit is organized into five sections:

  • Section I includes an overview of the toolkit and a short glossary. However, most terminology will be defined along the way.
  • Section II includes an introduction to evidence-based opioid prevention intervention, organized by four categories: public messaging campaigns, prescriber education, harm reduction, and other strategies.
  • Section III includes steps local boards of health can take to address opioid misuse, organized around the 10 Essential Public Health Services for Public Health Services.
  • Section IV includes a more in-depth case example showcasing how the Northampton Board of Health is integrating opioid prevention into its work.
  • Section V includes an annotated list of resources where readers can learn more about the prevention strategies included in this toolkit.

We do not anticipate that local health department staff will read this toolkit from start to finish. Instead, we anticipate staff familiarizing themselves with the menu of interventions available to them, then exploring opportunities to integrate these interventions into the important work they are already doing in their communities. Throughout the toolkit we provide examples of how cities and towns are approaching the opioid epidemic; we hope these will serve as helpful models.

Acknowlegements

This toolkit has benefited from the collective expertise and ideas of many individuals. In particular, the Massachusetts Health Officers Association would like to thank the following individuals for their thoughtful contributions:

  • Melanie Adler, Senior Project Director, Education Development Center
  • Aubrey Ciol, Program Director, Drug-Free Communities, Norwood, MA
  • Michele Farry, Regional Coordinator, Drug Addiction and Recovery Team, Northampton, MA
  • Derek Fullerton, Director of Public Health, Chief Health Strategist, Middleton, MA
  • Jessica Goldberg, Project Director Education Development Center
  • Stephanie Patton, Prevention Coordinator, Stoughton, MA
  • Erica Piedade, Director of Local Public Health Initiatives, Massachusetts Department of Public Health
  • Gisela Rots, Director, Project Director/Education Development Center, Center for Strategic Prevention Support
  • Ben Spooner, Associate Project Director, Education Development Center, Center for Strategic Prevention Support
  • Paul Williams, Former Substance Abuse Prevention Coordinator, Weymouth, MA

Defining Key Terms

This glossary is not comprehensive. Instead, it offers a starting point for ensuring a shared understanding of some selected key terms related to opioid use and overdose.

Opioids: Opioids are a class of drugs defined by their ability to bind to and activate opioid receptors in the body, primarily in the nervous and gastrointestinal systems. Their effects can relieve pain, reduce coughing, slow GI motility, depress respiration, and produce feelings of euphoria. Opioid drugs can be divided into the following categories: naturally occurring, synthetic, and semi-synthetic. Substances in each of these categories can include prescribed and non-prescribed drugs.

  • Naturally occurring opioids, also referred to as “opiates,” naturally occurring opioids are derived from poppy plants. They include morphine and codeine, which can be prescribed to treat acute pain or cough, and the illicit drug, heroin.
  • Synthetic opioids are manufactured in a laboratory and do not occur in nature. They include fentanyl and tramadol, both of which are used to treat pain. They can be produced as prescription medication and illicitly manufactured. Most fentanyl driving opioid-related overdose deaths in the United States is illicitly manufactured. Some prescription medications to treat opioid use disorder, methadone and buprenorphine, are also considered synthetic opioids.
  • Semi-synthetic opioids are derived from morphine and contain elements from chemical manufacturing in a laboratory. They include prescription medications like oxycodone, hydrocodone, hydromorphone, and oxymorphone. 

Opioid Overdose: An overdose is a lifethreatening physiological response to amount of an opioid or an opioid in a dangerous combination of other substances; it can be fatal or nonfatal. During an opioid overdose, a person’s breathing severely slows down and may stop. Other signs of an opioid overdose include small pupils, blue/purple lips or fingernails, and inability to wake up.

Opioid Use Disorder: A problematic pattern of opioid use that leads to serious impairment or distress. To be diagnosed with an opioid use disorder, a person must have two or more of the following symptoms within a 12-month period of time:

Loss of Control

Substance taken in larger amounts or for a longer time than intended

“I didn’t mean to start using so much.”

Persistent desire or unsuccessful effort to cut down or control use of a substance

“I’ve tried to stop a few times before, but I start using this drug again every time.”

Great deal of time spent obtaining, using, or recovering from substance use

“Everything I do revolves around using this drug.”

Craving (that is, a strong desire or urge) to use opioids

“I wanted to use so badly I couldn’t think of anything thing else.”

Social Problems

Continued opioid use that causes failures to fulfill major obligations at work, school, or home

“I keep having trouble at work/have lost the trust of friends and family because of using this drug.”

Continued opioid use despite causing recurrent social or personal problems

“I can’t stop using even though it’s causing problems with my friends/family/boss/landlord.”

Important social, occupational, or recreational activities are reduced because of opioid use

“I’ve stopped seeing my friends and family, and have given up my favorite hobby because of drugs.”

Risky Use

Recurrent opioid use in dangerous situations

“I keep doing things that I know are risky and dangerous to buy or use this drug.”

Continued opioid use despite related physical or psychological problems

“I know that using this drug causes me to feel badly/messes with my mind, but I still use anyway.”

Pharmacological Problems

Tolerance (that is, need to take higher doses of a drug to feel the same effects, or a reduced effect from the same amount)

“I have to take more and more of the drug to feel the same high.”

Withdrawal (the experience of pain or other uncomfortable symptoms in the absence of a drug)

“When I stop using the drug for a while, I’m in a lot of pain.”

Source: American Psychiatric Association. (2013). Substance Use Disorders. In Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.